The toad, also called the Colorado River toad, emits a “weak, low sound” and is one of the largest toads in North America, measuring nearly seven inches, the park service said, according to Fox’s local Fox affiliate . 35 Orlando. The toad secretes a powerful toxin that can sicken anyone who handles it or happens to get the toxin in their mouth, prompting the NPS to issue a warning about the amphibian. The Sonoran Desert Toad, also known as the Colorado River Toad, emits an illegal psychedelic substance that the National Park Service has advised against licking. (Credit: National Park Service) “As we say with most things you encounter in a national park, whether it’s a banana slug, an unknown mushroom or a large toad with glowing eyes in the night, don’t lick it,” the National Park Service said. ARIZONA BORDER OFFICERS STOP LOADS OF OVER 200,000 FENTANYL, COCAINE, METH PILLS HIDDEN IN VEHICLES The toad often lurks near springs, reservoirs, and streams in Mexico as well as parts of the American Southwest. Some people reportedly lick the animal to inhale its toxins, which contain a psychedelic chemical called 5-MeO-DMT that can induce an out-of-body experience. Close-up of a Colorado River toad, which the National Park Service recently advised against licking. (Freder via Getty Images) The psychedelic liquid is often extracted from the toad’s glands and then dried into a paste that can be smoked. CUSTOMS AND BORDER OFFICERS SEIZE $18.6 MILLION IN MED AT TEXAS POINT OF ENTRY: ‘OUTSTANDING DRUG INTERCEPTION’ “The experience will kick in within 10 to 30 seconds, and then you’ll be physically incapacitated for 20 to 30 minutes,” said Johns Hopkins psychedelic researcher Alan Davis. The US government has classified 5-MeO-DMT as a schedule 1 drug, meaning it has no accepted medical use. The US government has classified 5-MeO-DMT from the Colorado River frog as a schedule 1 drug, meaning it has no accepted medical use. (Mario Krpan via Getty Images) Smoking toad venom has gained popularity, with the likes of Mike Tyson and Hunter Biden admitting to using it to cure their drug addiction. CLICK HERE TO GET THE FOX NEWS APP The frog is considered endangered in New Mexico because of “collectors who want to use the animal for drug use,” among other factors, according to the state’s Game & Fish Department. California classifies the frog as endangered and has outlawed its poison, according to the Oakland Zoo. Jon Brown is a writer for Fox News Digital. Story tips can be sent to [email protected]